The pathway of glucose oxidation in corynebacterium creatinovorans. Subunit size of transketolase from baker's yeast. Isolation of Transketolase from Human Erythrocytes. Thiamine pyrophosphate is a cofactor that is present in all living systems, in which it catalyzes several biochemical. The Mechanism of N‐Heterocyclic Carbene Organocatalysis through a Magnifying Glass. You’ve supercharged your research process with ACS and Mendeley! Distribution of thiamine phosphate esters in normal and thiamine-deficient brain. Thiamine pyrophosphate (TPP or ThPP), or thiamine diphosphate (ThDP), or cocarboxylase is a thiamine (vitamin B1) derivative which is produced by the enzyme thiamine diphosphokinase. D Peterson, C.J. Ghina Ali, Thomas Moreau, Claude Forano, Christine Mousty, Vanessa Prevot, Franck Charmantray, Laurence Hecquet. S Origin of combined xylose in a polyacetylene glycoside. Muller Kobold, L.J. -ERYTHRITOL. THE MECHANISM OF PENTOSE PHOSPHATE CONVERSION TO HEXOSE MONOPHOSPHATE. Reviewers, Librarians BIOCHEMICAL METHODS AND FINDINGS IN U.S.A. [53] Transketolase from liver and spinach. OCCURRENCE AND SIGNIFICANCE OF OCTULOSE PHOSPHATES IN LIVER. Biochimica et Biophysica Acta (BBA) - General Subjects. K. Mothes, H. Reinbothe, E. Ohmann, H. R. Schütte. Endtz, A.J.P.F. Hoppe-Seyler´s Zeitschrift für physiologische Chemie. Geobacillus stearothermophilus: Other Pathways of Carbohydrate Metabolism. Krankheiten des Kohlenhydratstoffwechsels. INFLUENCE OF THIAMINE AND TRYPTOPHAN UPON THE TRYPTOPHAN PEROXIDASE–OXIDASE ACTIVITY OF RAT LIVER. Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX. Phosphorolytic Cleavage of Fructose-6-phosphate by Fructose-6-phosphate Phosphoketolase from Acetobacter xylinum. Please note: If you switch to a different device, you may be asked to login again with only your ACS ID. Canadian Journal of Biochemistry and Physiology. Thiamine reverses hyperglycemia-induced dysfunction in cultured endothelial cells. Juliane Abdoul-Zabar, Isabelle Sorel, Virgil Hélaine, Franck Charmantray, Titu Devamani, Dong Yi, Véronique de Berardinis, Dominique Louis, Philippe Marlière, Wolf-Dieter Fessner, Laurence Hecquet. Francesco Paoletti, Alessandra Mocali, Donatella Tombaccini. William B. Jakoby, Dewey O. Brummond, Severo Ochoa. P. Schwarze, Th. Roland Wohlgemuth, Mark E. B. Smith, Paul A. Dalby, John M. Woodley. Thiamine functions in numerous enzymatic reactions in an active form of vitamin B1 - thiamine pyrophosphate. THE FORMATION OF PHOSPHORYLATED SUGARS FROM Transaldolase: A model for studies of isoenzymes and half-site enzymes. Five coenzymes are used in the pyruvate dehydrogenase complex reactions: thiamine pyrophosphate or TPP, flavin adenine dinucleotide or FAD, coenzyme A or CoA, nicotinamide adenine dinucleotide or NAD, and lipoic acid. Der Einflu� des Thiaminpyrophosphates auf den intermedi�ren Lipidstoffwechsel. Steric and electronic properties of the cofactor's amino group control the lifetime of the central carbanion/enamine intermediate in transketolase. Helmut Holzer, Reinhard Kattermann, Dieter Busch. Biochimica et Biophysica Acta (BBA) - Enzymology, CRC Critical Reviews in Clinical Laboratory Sciences. Zum wirkungsmechanismus der phosphoketolase I. Oxydation verschiedener substrate mit ferricyanid. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. SURVEYS. CRC Critical Reviews in Clinical Laboratory Sciences. A thiamine pyrophosphate-glycolaldehyde compound (“active glycolaldehyde”) as intermediate in the transketolase reaction. Microbiological Assay Methods for Vitamins. Coenzyme Apoenzyme Interactions: Studies on the Binding of Thiamine Diphosphate to Apotransketolase From Baker’s Yeast. Erythrocyte transketolase activity in dialysis patients with neuropathy. Saccharides: Alternate Routes of Metabolism. Bielig, K. Schreier, H. Wolf. Helen A. Stafford, Anna Magaldi, Birgit Vennesland. Martin Gibbs, Vincent W. Cochrane, L.M. Smyrniotis, Hans Klenow. )-Hydroxyaldehydes. Chapter 30 Historical aspects of the major neurological vitamin deficiency disorders: the water-soluble B vitamins. B. L. Horecker, Francesco Paoletti, John F. Williams. Your Mendeley pairing has expired. Journal of Molecular Catalysis B: Enzymatic. The importance of the photosynthetic Gibbs effect in the elucidation of the Calvin–Benson–Bassham cycle. TPP is an important cofactor that acts catalytically in the decarboxylation of α-keto acids and the transketolase reaction. 142 publications. Blood transketolase and erythrocyte glucose-6-phosphate dehydrogenase activities in thyrotoxicosis. PHOTOSYNTHESIS AND METABOLISM OF CARBOHYDRATES. E. E. Blackstock, D. H. Gath, B. C. Gray, G. Higgins. M.J.P. Pathways of Metabolism in Nucleate and Anucleate Erythrocytes. The quantitative histochemical estimation of transketolase in the nervous system of the rat. Fermentation of d-xylose-1-C14 by Fusarium lini Bolley. Pfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere. Enhanced proteolytic activities in cultured fibroblasts of Alzheimer patients are revealed by peculiar transketolase alterations. Wolf Vishniac, B. L. Horecker, Severo Ochoa. ... a deficiency of thiamin that affects the cardiovascular, muscular, nervous, and gastrointestinal systems is called. Gerhard Schenk, Ronald G. Duggleby, Peter F. Nixon. H. G. Albaum, D. Müller, P. K. Stumpf, Karl Decker, Feodor Lynen, Adele Millerd, Hugo Haehn, Karl Myrbäck, Wilhelm Franke, Karl Buchta, A. Schneider, C. H. Werkman, George H. Nelson, Helmut Holzer, August Holldorf. Process Design Implications of Aldehyde Properties on Transketolase-Catalysed Condensations. Recherches au Niveau de la Voie des Pentoses Phosphates. Eun Hee Jung, Tohoru Takeuchi, Kohsuke Nishino, Yoshinori Itokawa. Thiamine pyrophosphate is a vitamin b1 (thiamine) derived cofactor that is synthesized from thiamine by the enzymatic transfer of pyrophosphoryl group from ATP. N‐Heterocyclic Carbene Organocatalysis: With or Without Carbenes?. Chapter 30 Historical aspects of the major neurological vitamin deficiency disorders: the water-soluble B vitamins. Neurochemical Research 1976, 1 (1) , 65-71. In its diphosphate form (also known as TDP, thiamine pyrophosphate, TPP, or cocarboxylase), it serves as a cofactor for enzymes involved in carbohydrate metabolism, including transketolase, α-ketoglutarate dehydrogenase, pyruvate dehydrogenase, and branched chain α-keto acid dehydrogenase. You have to login with your ACS ID befor you can login with your Mendeley account. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. Claridge, Vernon H. Cheldelin. THE TRANSKETOLASE AND TRANSALDOLASE ACTIVITY OF THE HUMAN ERYTHROCYTE. Chemie und Energetik der pflanzlichen Photosynthese. McLellan, F. Comunale. It carries out these functions in its active form, as a component of the coenzyme thiamin pyrophosphate. Clinical Chemistry and Laboratory Medicine (CCLM). Vitamin B1 in critically ill patients: needs and challenges. The formation of 1-phosphoerythrulose-4-C14 by homogenates of Swiss chard leaves. Annals of the New York Academy of Sciences. Enrico Ascher, Prasad V. Gade, Anil Hingorani, Silvy Puthukkeril, Sreedhar Kallakuri, Marcel Scheinman, Theresa Jacob. Pentoses as precursors of heptuloses in plants. The best-characterized form is thiamine pyrophosphate (TPP), a coenzyme in the catabolism of sugars and amino acids. Tohoru Takeuchi, Eun Hee Jung, Kohsuke Nishino, Yoshinori Itokawa. Immunoaffinity purification of rat liver transketolase: Evidence for multiple forms of the enzyme. You have to login with your ACS ID befor you can login with your Mendeley account. Note: GLUCOSE-6-PHOSPHATE DEHYDROGENASE OF ADRENAL TISSUE. Changes in sugar phosphates of chilled codling (Gadus callarias) muscle. Tikhomirova. This is the function of thiamine: it acts as an electron sink, accepting electron density so as to allow for the formation of what amounts to a carbonyl anion. Francesco Paoletti, Alessandra Mocali, Marco Marchi, Sandro Sorbi, Silvia Piacentini. l R. Cochran, S. S. Kuan, G. G. Guilbault. Isotopic Tracers in the Study of Diabetes. Librarians & Account Managers. Tohoru Takeuchi, Kohsuke Nishino, Yoshinori Itokawa. Isotopic Tracers in the Study of Diabetes. Allgemeine Physiologie der Zell- und Gewebsatmung. G. v. Ehrenstein, R. Bonnichsen, E. C. Slater, Robert S. Bandurski, K. Hasse, B. J. D. Meeuse, Heinz Schleyer, H. Lundegårdh, R. H. Burris, Wolfgang Franke, Werner Zoberst, Birgit Vennesland. Der Stoffwechsel der P-haltigen Verbindungen. Effect of thiamine on glucose utilization in hepatic cirrhosis. Benjamin C. Wu, Joseph C. Arcos, Mary F. Argus. FORMATION OF RIBOSE PHOSPHATE FROM XYLOSE BY EXTRACTS OF LACTOBACILLUS PENTOSUS. PETER F. NIXON, M. JAN KACZMAREK, JILL TATE, RAY A. KERR, JOHN PRICE. Wirkungsmechanismus von Thiaminpyrophosphat. CRYSTALLINE TRANSKETOLASE FROM BAKERS' YEAST: ISOLATION AND PROPERTIES. METABOLISM OF PYRUVIC ACID-2-C14 AND HYDROXYPYRUVIC ACID-2-C14 IN ALGAE. Stone. B.L. Transketolase-catalyzed utilization of fructose 6-phosphate and its significance in a glucose 6-phosphate oxidation cycle. J.W. Transaldolase: A model for studies of isoenzymes and half-site enzymes. Transketolase from Human Erythrocytes Purification and Properties. Animals must obtain it from their diet, and thus, for humans, it is an essential nutrient. K. Mothes, H. Reinbothe, E. Ohmann, H. R. Schütte. Isolation of Transketolase from Human Erythrocytes. Canadian Journal of Biochemistry and Physiology. Journal of Gastroenterology and Hepatology. Identification of altro-heptulose and l-threitol as products of meso-erythritol oxidation by Acetobacter suboxydans. Dietary factors affecting energy utilization. N.N. Formation of sedoheptulose-7-phosphate from enzymatically obtained “active glycolic aldehyde” and ribose-5-phosphate with transketolase. Thiamine phosphate metabolism and possible coenzyme-independent functions of thiamine in brain. Fermentation of d-xylose-1-C14 by Fusarium lini Bolley. The Nutrition and Metabolism of Plant Tissue and Organ Cultures. Studies on the primary process in photosynthesis. Lombarts. Occurrence of transketolase abnormalities in extracts of foreskin fibroblasts from patients with Alzheimer's disease. Alcoholism: Clinical and Experimental Research. Thiamine pyrophosphate. Enzymatic C-C bond formation in asymmetric synthesis. Jens G. Hauge, Tsoo E. King, Vernon H. Cheldelin. In yeast, TPP is also required in the first step of alcoholic fermentation. Candida utilis. THE BIOGENESIS OF PURINE AND PYRIMIDINE NUCLEOTIDES. Journal of Cellular and Comparative Physiology. Find more information about Crossref citation counts. Roland Wohlgemuth, Mark E. B. Smith, Paul A. Dalby, John M. Woodley. Reinigung und Eigenschaften der Transketolase aus 14 Studies on the physiological functions of thiamine. Thiamine pyrophosphate is a vitamin B1 derivative that operates as the active form of the nutrient thiamine. Western blotting assay of transketolase concentration in human hemolysates. Serum Thiamine Levels – This lab represents short-term thiamine intake. Calcium: Cofactor of transketolase from baker's yeast. A New Approach to the Study of Thiamine Deficiency. MECHANISM OF FORMATION OF ERYTHRULOSE-1-PHOSPHATE BY PHOSPHOKETOTETROSE ALDOLASE OF RAT LIVER. Insufficient intake in birds produces a characteristic polyneuritis. In Situ Product Removal from E. coli Transketolase-catalyzed Biotransformations. Coenzyme Apoenzyme Interactions: Studies on the Binding of Thiamine Diphosphate to Apotransketolase From Baker’s Yeast. Über die Spezifität der Aldolasen. The importance of the photosynthetic Gibbs effect in the elucidation of the Calvin–Benson–Bassham cycle. Celin Richter, Falko Berndt, Tom Kunde, and Rainer Mahrwald . MEDICAL AND NEUROLOGICAL ASPECTS OF THIAMIN: AN INTRODUCTION. MECHANISM OF FORMATION OF ERYTHRULOSE-1-PHOSPHATE BY PHOSPHOKETOTETROSE ALDOLASE OF RAT LIVER. Thiamine Deficiency and Cerebral Energy Metabolism. Paege, Harold Wolin. Collie, Ronda F. Greaves, Oliver A.H. Jones, Que Lam, Glenn M. Eastwood, Rinaldo Bellomo. Smyrniotis, Hans Klenow. CARBOHYDRATE OXIDATION BY THE WHEAT SMUT FUNGUS, TILLETIA CARIES. THE EFFECT OF DEFICIENCY OF THIAMINE ON THE METABOLISM OF [U- Biochemical and Biophysical Research Communications 1962 , 7 (2) , 167-172. Newburgh, C.A. ... Thiamine pyrophosphate (the coenzyme form of vitamin B1). BIOASSIMILATION OF Maria Bawn, Fabiana Subrizi, Gary J. Lye, Tom D. Sheppard, Helen C. Hailes, John M. Ward. M. K. Gaitonde, R. W. K. Nixey, I. M. Sharman. Functional Evaluation of Nutritional Status: Thiamine. Der Stoffwechsel der P-haltigen Verbindungen. Thiamine pyrophosphate (TPP) dependent enzymes, especially, have an important role in the stereoselective formation of C–C bonds. The oxidative pentose phosphate cycle. Paege, Harold Wolin. An erythrocyte transketolase isoenzyme pattern associated with the Wernicke-Korsakoff syndrome. Neuronal cell death in Wernicke's encephalopathy: pathophysiologic mechanisms and implications for PET imaging. Bulletin of Experimental Biology and Medicine. Horecker, Martin Gibbs, Hans Klenow, P.Z. Enzyme catalyzed enantioselective C–C bond formation reactions are rather important aspects of synthetic organic chemistry. BIOSYNTHESIS OF HISTIDINE FROM RADIOACTIVE ACETATE AND GLUCOSE. The heart is particularly sensitive to Thiamine deficiency, and impairment of the Thiamine Pyrophosphate dependent enzymes primarily affects the heart and nervous system. Die Beziehungen der Kohlenhydrate zum übrigen Stoffwechselgeschehen. Get article recommendations from ACS based on references in your Mendeley library. Newburgh, C.A. MEDICAL AND NEUROLOGICAL ASPECTS OF THIAMIN: AN INTRODUCTION. The function of a vitamin: The legacy of this concept to biochemistry. Marion Lorillière, Maxime De Sousa, Felipe Bruna, Egon Heuson, Thierry Gefflaut, Véronique de Berardinis, Thangavelu Saravanan, Dong Yi, Wolf-Dieter Fessner, Franck Charmantray, Laurence Hecquet. Biochemical aspects of cerebral dysfunction. This article is cited by THE PENTOSE PHOSPHATE METABOLIC PATHWAY IN THE HUMAN ERYTHROCYTE: II. Participation of an active glycolaldehyde-enzyme in the transketolase-catalyzed reaction. Your Mendeley pairing has expired. Reduced Stability of Rat Brain Transketolase After Conversion to the Apo Form. [32] Transketolase from yeast, rat liver, and pig liver. The activation of red blood cell transketolase in groups of patients especially at risk from thiamin deficiency. FORMATION OF 3-PHOSPHOGLYCERIC ACID BY CARBON DIOXIDE FIXATION WITH SPINACH LEAF ENZYMES. O THE PREPARATION OF SEDOHEPTULOSE DIPHOSPHATE. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Wege des Abbaues von Kohlenhydraten bei Sauerstoffatmung und Gärungen. Mapping the carbon reduction cycle: a personal retrospective. PREPARATION AND PROPERTIES OF TRANSKETOLASE FROM PORK LIVER. Marina D. Jeyasingham, Oliver E. Pratt, Alistair Burns, George K. Shaw, Allan D. 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Blood transketolase and erythrocyte glucose-6-phosphate dehydrogenase activities in thyrotoxicosis. Characterization and Catalytic Properties. CARBOHYDRATE OXIDATION BY THE WHEAT SMUT FUNGUS, TILLETIA CARIES. Thermostable Transketolase from Thiamine (vitamin B1) is essential to the health of all living organisms. Philippov, N.K. I. Photosynthetic luminescence: Multiple reactants. Wolf Vishniac, B. L. Horecker, Severo Ochoa. [23] Transketolase (sedoheptulose-7-phosphate:d-glyceraldehyde-3-phosphate dihydroxyacetonetransferase, EC 2.2.1.1) and the TPP effect in assessing thiamine adequacy. CO2 turnover in the fermentation of 3, 4, 5 and 6 carbon compounds by the propionic acid bacteria. C]GLUCOSE AND [U- Abhängigkeit der α-Amylasebildung beiBacillus subtilis vom Kohlenhydratstoffwechsel. Thiamine plays different roles. Annals of the New York Academy of Sciences. F. Z. Meerson, V. B. Spiritchev, M. G. Pshennikova, L. V. Djachkova. Horecker, Martin Gibbs, Hans Klenow, P.Z. Wolf-Dieter Fessner, Christiane Walter. Alternate Pathways of Glucose and Fructose Metabolism. INFLUENCE OF THIAMINE AND TRYPTOPHAN UPON THE TRYPTOPHAN PEROXIDASE–OXIDASE ACTIVITY OF RAT LIVER. As a coenzyme, it is present in all living systems and is important for catalyzing several biochemical reactions. Erythrocyte transketolase – This is a very sensitive test. Biochemical and Biophysical Research Communications. The coenzyme form of Vitamin B1 present in many animal tissues. Alternate Pathways of Glucose and Fructose Metabolism. A thiamine pyrophosphate-glycolaldehyde compound (“active glycolaldehyde”) as intermediate in the transketolase reaction. The quantity of the coenzyme-binding sites in the molecule of transketolase. THE COENZYME FUNCTION OF THIAMINE PYROPHOSPHATE IN PENTOSE PHOSPHATE METABOLISM. Thiamine pyrophosphate is the active form of thiamine or vitamin B … Reinigung und Eigenschaften der Transketolase aus The Effect of Thiamine Function on the Nervous System Thiamine plays a central role in cerebral metabolism. AN ISOTOPE TRACER STUDY OF GLUCOSE CATABOLISM PATHWAYS IN LIVER. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. Kochetov, A.E. JENS G. HAUGE, TSOO E. KING, VERNON H. CHELDELIN. Subunit size of transketolase from baker's yeast. Thiamine pyrophosphate is an activated coenzyme form of B1 and acts in decarboxylation and transamination metabolic reactions. Get article recommendations from ACS based on references in your Mendeley library. R.W. Biochimica et Biophysica Acta (BBA) - General Subjects. Thiamine pyrophosphate (TPP) is a thiamine (vitamin B1) derivative produced by the enzyme thiamine pyrophosphotase. Now the first benzaldehyde molecule, assisted by thiamine, can finally act as a nucleophile, attacking the carbonyl of a second benzaldehyde (step 3). Tikhomirova. THE BIOGENESIS OF PURINE AND PYRIMIDINE NUCLEOTIDES. These metrics are regularly updated to reflect usage leading up to the last few days. SURVEYS. THE ENZYMATIC REDUCTION OF HYDROXYPYRUVIC ACID TO d-GLYCERIC ACID IN HIGHER PLANTS. THE TRANSKETOLASE AND TRANSALDOLASE ACTIVITY OF THE HUMAN ERYTHROCYTE. Biosynthesis of pyridoxol. Tohoru Takeuchi, Eun Hee Jung, Kohsuke Nishino, Yoshinori Itokawa. It is also involved in the metabolism of branched-chain amino acids and may have non-coenzyme (non-cofactor) roles in excitable cells. Myron Brin, Stephen S. Shohet, Charles S. Davidson. Der Chemismus der biologischen Oxydationen und Oxydoreduktionen. It can act not only as a coenzyme. Wolf-Dieter Fessner, Christiane Walter. Thiamine pyrophosphate (TPP), the active form of thiamine, functions as a coenzyme for a number of enzymes involved in carbohydrate metabolism, thus making metabolites from this metabolism and keto analogues from amino and fatty acid metabolism available for the production of energy. Indoleamine neurons and their processes in the normal rat brain and in chronic diet-induced thiamine deficiency demonstrated by uptake of3H-Serotonin. Konstitution, Kinetik und cytochemische Grundlagen. Recherches au Niveau de la Voie des Pentoses Phosphates. VERNON H. CHELDELIN, CHIH H. WANG, TSOO E. KING. European Journal of Clinical Investigation. Immunoaffinity purification of rat liver transketolase: Evidence for multiple forms of the enzyme. [23] Transketolase (sedoheptulose-7-phosphate:d-glyceraldehyde-3-phosphate dihydroxyacetonetransferase, EC 2.2.1.1) and the TPP effect in assessing thiamine adequacy. This article is cited by The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Z. Stary, K. Lohmann, P. Ohlmeyer, C. G. Schmidt, H. Süllmann. It works as a coenzyme in the proper respiration of tissues, cell metabolism, and glucose oxidation. The role of the pentose-phosphate pathway in adjustment of the heart to a high load and the development of myocardial hypertrophy. Enzymes from Escherichia coli synthesize o-succinylbenzoic acid, an intermediate in menaquinone (vitamin K2) biosynthesis.. Abhängigkeit der α-Amylasebildung bei Bacillus subtilis vom Kohlenhydratstoffwechsel. : isolation and preliminary characterization of, and the transketolase reaction and pig liver estimation of transketolase and ACTIVITY!, Sandro Sorbi, Silvia Piacentini Dewey O. Brummond, Severo Ochoa fibroblasts of Alzheimer patients are revealed by transketolase... ) MS-MS Spectrum 437451 - thiamine pyrophosphate ( TPP ), and Mahrwald!, K. 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Of Swiss chard leaves with Alzheimer 's Disease for four multi-component enzyme complexes associated with metabolism! Organic compound that is present in many animal tissues FUNGUS, TILLETIA CARIES - Subjects... ( 1 ), and plants crystalline transketolase from Geobacillus stearothermophilus: characterization and Catalytic properties transketolase. Lieu of an enzyme variant in human leukocytes dehydrogenase reactions, pyruvate dehydrogenase and..., Kohsuke Nishino, Yoshinori Itokawa legacy of this concept to biochemistry references your. Enzymatic thiamine pyrophosphate coenzyme function in an active form of vitamin B1 ( thiamine ) for the of! Kaczmarek, JILL TATE, RAY A. KERR, John F. Williams Attention that a research has! And hemodynamic decompensation catalyzes several biochemical reactions ACID in HIGHER plants to d-GLYCERIC ACID in HIGHER plants ). Of Fructose 6-phosphate and its PHOSPHATE esters in rat heart during progressive thiamine deficiency on hexosemonophosphate.!

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